Primary pulmonary hypertension is a lung disorder that causes the blood pressure in a personâ€™s pulmonary artery to rise above acceptable levels. This is also a condition that is believed to be inherited while at the same time it is also true that no real causes of the condition have as yet been discovered. Primary pulmonary hypertension was first reported more than a century ago when in the year 1891 a case was identified in which the autopsy of the patient showed thickening of the deceased personâ€™s pulmonary artery.
Later, in the year 1951 another thirty-nine cases were reported and this time there was an indication that the patient was also suffering from lung and heart disease and it was then that the term primary pulmonary hypertension was coined to describe such a condition. During the period 1967 through 1973 there was an increase in primary pulmonary hypertension cases that affected people living in Central Europe and after much study and investigation the reason for this increase was identified as being consuming of an amphetamine drug called aminorex fumarate which was used by people to control their appetites. Subsequently, aminorex fumarate was withdrawn from the European market and consequently there was a corresponding decline in cases of primary pulmonary hypertension.
In the recent past, France as well the United States has seen primary pulmonary hypertension being associated with taking of appetite suppressants such as dexfenfluramine and fenfluramine that were then removed from the market in the year 1997.
The main cause of primary pulmonary hypertension seems to be genetic or some other unknown reason. According to research findings it was discovered that blood vessels can be very sensitive to some internal as well as external factors and when these factors affect the blood vessels it causes them to contract or narrow down.
The symptoms of primary pulmonary hypertension include fatigue, dyspnea or difficulties in breathing, dizziness, fainting spells, edema or swollen ankles or legs, cyanosis or bluish colored skin and lips, angina or chest pain and racing pulse. The more severe symptoms of primary pulmonary hypertension include not being able to perform everyday and even minimal activities, and in addition the patient also risks becoming bedridden.
Pulmonary arterial hypertension is in fact a very serious ailment which must be treated at the earliest. However, as of now no known cure for it has been discovered and furthermore the disease can be caused by other secondary conditions such as rheumatic diseases.